Non-Malaysian citizens are subject to 6% SST, to be verified and paid at the counter before screening.
Protein C is a vitamin K–dependent glycoprotein synthesized in the liver, acting as a natural anticoagulant. Once activated into Activated Protein C (APC), it degrades clotting factors Va and VIIIa, preventing excessive clotting and maintaining balance.
Protein C deficiency increases the risk of venous thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism.
A venous blood sample is collected to measure Protein C activity or antigen level. Interpretation should include coagulation profile, Protein S, and clinical data.
Q1: Does Protein C deficiency always cause thrombosis?
A: Not always, but it significantly increases venous thromboembolism risk and requires clinical assessment.
Q2: What is the relationship between Protein C and Protein S?
A: Protein C works together with Protein S as a cofactor. Deficiency in either increases clotting risk.
Q3: What conditions can cause temporary Protein C reduction?
A: Acute thrombosis, infection, liver dysfunction, or use of warfarin and other anticoagulants.